
Psychiatric medications are often described in simple terms — “antidepressants boost mood” or “antipsychotics reduce delusions.” But the science behind these treatments is far more nuanced. At Alessi Psychiatry and Life Center in Ann Arbor, Michigan, Dr. Norman Alessi applies more than 40 years of clinical and academic expertise to ensure psychopharmacology is used with precision, safety, and deep understanding of how medications truly affect the brain.
The Role of Neurotransmitters
The brain communicates through chemical messengers known as neurotransmitters. When these signaling systems are disrupted, symptoms such as depression, anxiety, or psychosis can emerge. Medications work by modifying the way neurotransmitters are released, received, or broken down.
For example, selective serotonin reuptake inhibitors (SSRIs) increase the availability of serotonin in the brain, often easing depressive symptoms. Mood stabilizers like lithium can regulate the excitability of neurons, reducing the risk of mood swings in bipolar disorder. Antipsychotics primarily act on dopamine pathways to help quiet intrusive thoughts or hallucinations. Each class of medication targets specific brain circuits, but the ultimate goal is to restore balance rather than simply suppress symptoms.
Why Tailoring Matters
Although two patients may carry the same diagnosis, their neurochemistry (and therefore their response to medication) may differ. One individual may benefit from an SSRI, while another might respond better to a serotonin-norepinephrine reuptake inhibitor (SNRI). Genetics, medical history, trauma exposure, and developmental stage all influence how medications work in a given person.
This is where Dr. Alessi’s depth of experience becomes critical. As a Professor Emeritus of the University of Michigan and a nationally recognized leader in psychiatry, he approaches psychopharmacology as part of a comprehensive strategy rather than a quick fix. Each prescription is carefully considered in the context of psychotherapy, family environment, and, when appropriate, innovative options like ketamine-assisted psychotherapy.
Balancing Science with Care
The field of psychopharmacology is always advancing, with new medications targeting glutamate and other emerging pathways. At Alessi Psychiatry, scientific knowledge is paired with compassion and individualized care. Medications are not prescribed as a stand-alone solution but as one component of a broader treatment plan designed to foster stability, resilience, and healing.
Expert Care for Complex Cases
For patients whose symptoms have resisted standard treatments, or for children and adolescents with developing brains, precision in medication management is essential. By combining rigorous diagnostic assessment with decades of psychopharmacological expertise, Dr. Alessi and his team help patients achieve meaningful progress.
If you or a loved one is considering psychiatric medications and wants care rooted in both science and compassion, contact Alessi Psychiatry and Life Center in Washtenaw County at (734) 222-6222 to schedule a consultation.